2-Trimethylsilylethylsulfonyl chloride, SES-Cl
2-(TRIMETHYLSILYL)ETHANESULFONYL CHLORIde
CAS: 106018-85-3
Molecular Formula: C5H13ClO2SSi
2-Trimethylsilylethylsulfonyl chloride, SES-Cl - Names and Identifiers
2-Trimethylsilylethylsulfonyl chloride, SES-Cl - Physico-chemical Properties
| Molecular Formula | C5H13ClO2SSi |
| Molar Mass | 200.76 |
| Density | 1.059 g/mL at 25 °C |
| Boling Point | 146.8 °C/760 mmHg |
| Flash Point | 21°C |
| Solubility | Sol most common organic solvents. |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.4444 |
2-Trimethylsilylethylsulfonyl chloride, SES-Cl - Risk and Safety
| Risk Codes | R11 - Highly Flammable R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | UN 1993 3/PG 2 |
| WGK Germany | 3 |
2-Trimethylsilylethylsulfonyl chloride, SES-Cl - Introduction
2-(Trimethylsilyl) ethanesulfonyl chloride, chemical formula C6H15ClO2SSi, is an organosilicon compound. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless or yellowish liquid
-Density: approx. 1.1g/cm³
-Melting point:-31°C
-Boiling point: about 107-110°C
-insoluble in water, soluble in some organic solvents, such as alcohols, ethers, aromatics, etc.
Use:
2-(trimethylsilyl) ethane sulfonyl chloride is usually used as a reagent in chemical reactions and is widely used in organic synthesis, mainly for the following aspects:
-As a chlorinating agent, it is used in the sulfonyl chloride reaction in the reaction.
-As a reagent with nucleophilic offensive properties, it can be used for esterification, acylation and sulfonylation reactions.
-used as sulfonyl chloride reagent, plays an important role in drug synthesis and natural product synthesis.
Preparation Method:
The preparation of 2-(trimethylsilyl) ethanesulfonyl chloride can be carried out by the following steps:
1.2-(dimethylsilyl) ethane sulfonyl chloride is obtained from the reaction of dimethylethane and thionyl chloride.
2.2-(Dimethylsilyl) ethane sulfonyl chloride is further reacted to obtain 2-(trimethylsilyl) ethane sulfonyl chloride.
Safety Information:
- 2-(trimethylsilyl) ethanesulfonyl chloride is irritating to eyes, skin and respiratory tract, please avoid direct contact.
-When using, please take appropriate safety measures, including wearing protective gloves, goggles and respiratory protection equipment.
-Avoid contact with oxidants and strong alkali substances to prevent dangerous reactions.
-The compound should be stored in a well-ventilated place and away from ignition and igniting objects.
Please note that when using and handling any chemical substances, you should follow relevant safety procedures and carefully read the safety data sheet (MSDS) provided by the supplier.
Nature:
-Appearance: colorless or yellowish liquid
-Density: approx. 1.1g/cm³
-Melting point:-31°C
-Boiling point: about 107-110°C
-insoluble in water, soluble in some organic solvents, such as alcohols, ethers, aromatics, etc.
Use:
2-(trimethylsilyl) ethane sulfonyl chloride is usually used as a reagent in chemical reactions and is widely used in organic synthesis, mainly for the following aspects:
-As a chlorinating agent, it is used in the sulfonyl chloride reaction in the reaction.
-As a reagent with nucleophilic offensive properties, it can be used for esterification, acylation and sulfonylation reactions.
-used as sulfonyl chloride reagent, plays an important role in drug synthesis and natural product synthesis.
Preparation Method:
The preparation of 2-(trimethylsilyl) ethanesulfonyl chloride can be carried out by the following steps:
1.2-(dimethylsilyl) ethane sulfonyl chloride is obtained from the reaction of dimethylethane and thionyl chloride.
2.2-(Dimethylsilyl) ethane sulfonyl chloride is further reacted to obtain 2-(trimethylsilyl) ethane sulfonyl chloride.
Safety Information:
- 2-(trimethylsilyl) ethanesulfonyl chloride is irritating to eyes, skin and respiratory tract, please avoid direct contact.
-When using, please take appropriate safety measures, including wearing protective gloves, goggles and respiratory protection equipment.
-Avoid contact with oxidants and strong alkali substances to prevent dangerous reactions.
-The compound should be stored in a well-ventilated place and away from ignition and igniting objects.
Please note that when using and handling any chemical substances, you should follow relevant safety procedures and carefully read the safety data sheet (MSDS) provided by the supplier.
Last Update：2024-04-09 15:17:50
